Currently Instructed Courses

Applied Physics 291 : Electron Microscopy 

Harvard College/GSAS: 1761


David C. Bell

Meeting time: M., 2-3:30, and a three-hour laboratory session to be arranged.

Exam group: 7,8

Lectures and laboratory instruction on transmission electron microscopy(TEM) and Cs corrected, aberration-correction microscopy and microanalysis. Lab classes include; diffraction, dark field imaging, X-ray spectroscopy, electron energy-loss spectroscopy, atomic imaging, materials sample preparation, polymers, and biological samples.

Biophysics 242r: Special Topics in Biophysics

Harvard College/GSAS: 6011


James M. Hogle (Medical School) and David C. Bell
Location: Biological Labs 1058
Meeting Time: Tu., Th., 10–11:30
Exam Group: 12,13
New Biophysical topics emerging from research in faculty laboratories, topics in areas of special interest not normally available in the established curriculum. This focus on Electron Microscopic methods including TEM,STEM, SEM, etc.
Note: Weekly lectures with discussion sections.

Nanofabrication and Nano-analysis

Harvard Extension School: ENSC E-131 (13629)


David C. Bell PhD, Professor, Harvard University - Jiangdong Deng PhD, Principal Scientist, Center for Nanoscale Systems, Harvard University
Location: LISE 303
Meeting Time: Thursday 7:35pm - 9:35pm
This laboratory course explores the concepts of nanotechnology through classic nanofabrication and nano-analysis. Through nanofabrication we introduce two approaches to fabricate nanoscale devices and materials: bottom-up nanofabrication and top-down nanofabrication. Bottom-up fabrication forms device structures directly from mechanisms of material growth such as atomic layer deposition methods. Top-down nanofabrication produces nanometre scale devices from bulk materials by lithography techniques, which include photolithography and e-beam lithography. Several analysis techniques are introduced including, for example, scanning electron microscopy, transmission electron microsocopy, and x-ray microanalysis applied to simple devices and structures as fabricated in class. Prerequisite: students must pass the required safety training for cleanroom use.
Note: Graduate credit $1,900.
See http://www.extension.harvard.edu

Microfluidics Applications for Biological Analysis and Discovery

Harvard Extension School: ENSC E-156 (23272)


David C. Bell PhD, Professor Applied Physics, Harvard University

Location: LISE 303

Meeting time: Monday 7:35pm - 9:35pm

This is a laboratory course that allows students to fabricate samples and a microfluidic device of their own. The course covers the concepts of design, testing, and prototyping for a microfluidic device, and also incorporates basic microscopy training for biological materials. Prerequisite: ENSC E-155, which may be taken concurrently.

See http://www.extension.harvard.edu


Nanotechnology for Drug Discovery and Delivery

Harvard Extension School: ENSC E-151 (23684)


David C. Bell PhD, Professor  on Applied Physics, Harvard University

Location: LISE 303

Meeting time: Tuesday 7:35pm - 9:35pm

This is a hands-on laboratory that allows students to use and explore the nanoscale world with leading edge research equipment. It includes sample preparation of biological materials as well as training to use optical fluorescence, scanning, and transmission electron microscopes to examine the nanoscale world. Prerequisite: ENSC E-150, or the equivalent.

See http://www.extension.harvard.edu

BIOS E-170 Introduction to Microscopy


This comprehensive course on microscopy techniques introduces students to both the theory and practical use of modern microscopes. The course features lectures on the basic physical principles behind the most common modern microscopy techniques. We cover introduction to optics, principles of image formation, light microscopy techniques, principles of fluorescence, digital imaging, confocal microscopy, TIRF, STORM/PALM, STED, FRET-FLIM, and FRAP techniques, structured illumination, two-photon fluorescence, second harmonic generation, vibrational imaging, scanning probe microscopy (SPM) techniques, atomic force microscopy (AFM), electron microscopy (SEM, TEM and STEM), and X-ray microscopy/microCT. The lectures are reinforced with the laboratory sessions featuring extensive demonstrations and hands-on exercises on a wide variety of microscopes. These sessions are held in the state-of-the-art laboratories of the Center for Nanoscale Systems (CNS) at Harvard University. This course is designed to provide students and researchers from various fields a comprehensive and practical introduction to modern microscopy techniques and a background in modern optical research tools. (4 credits)
Prerequisite(s): one year each of college-level calculus and physics, or permission of the instructors.
David C. Bell, PhD. Gordon McKay Professor of the Practice of Electron Microscopy, Harvard University.
Turgut Fettah Kosar, PhD. Manager and Principal Scientist, Center for Nanoscale Systems, Harvard University.
Arthur McClelland, PhD. Senior Microscopy Scientist at the Center for Nanoscale Systems, Harvard University.
Class times: Wednesdays beginning Sept. 3, 5:30-7:30 pm.
Course tuition: undergraduate credit $1,250, graduate credit $2,200.
Limited enrollment.